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Pharmaceutical biotech manufacturing clean room

Case Study · Pharmaceuticals

Production Scheduling Transformation: Enhancing Manufacturing Operations with Industrial Intelligent Application(MES)

01 — BACKGROUND

​ A UK-based biotech leader in allergy immunotherapy vaccines sold across 9 EU countries. 500+ staff operating an 11k m² MHRA-certified plant specializing in high-precision manufacturing.

02 — The Challenge

Coordination of Multi-Line Production Planning

01

Excel-only Planning

4–6 hours of daily manual effort required to build schedules across multi-line, multi-shift production.

02

Rush/Insert Orders

Emergency orders forced full sheet rewrites, causing 2–3 hours of lost time and WIP & materials misalignment.

03

Info Lag

Updated schedules were printed/emailed; 300 operators received changes with a 30–60 minute delay.

04

Inventory Risk

Expiry-sensitive bulk vaccines faced over-production risks, tying up critical working capital.

03 — The Solution

Industrial Intelligent Scheduling

Vaccine vials production line

ERP Plug-in

Auto-pulls production tasks from split orders; no other interfaces required.

Smart Rule Engine

Advanced logic considering workstation capacity, item rules, and process stage sequences (including expiry); generates optimal weekly sequences in < 5 seconds.

Planner Cockpit

Gantt drag-and-drop for manual tweaks; system re-optimizes only the impacted blocks.

Hot-Order Button

One-click re-run; new plans pushed to lines instantly while previous frozen sections remain locked.

Shop-Floor View

Real-time visibility of current step and next step; automatic version control for all 300+ operators.

04 — Key Performance

​

Faster Scheduling

99%

Plan generation time slashed from 4 hours to 5 minutes.

Reactivity

<5min

Rush orders are processed and synchronized instantly across the facility.

Sync Delays

0

Real-time synchronization achieved for all 300 staff members.

Compliance

GMP

Strategic advancement in digital manufacturing while maintaining strict regulatory standards.

05 — Client Quote

“
The Intelligent Application let us take a giant step in digital manufacturing while keeping GMP compliance.

—Team